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Impaired lysosomal flux or sustained oxidative stress, for instance, can convert autophagy from a protective mechanism into a driver of lysosomal dysfunction, mitochondrial stress and neuronal vulnerability 147,148
Katona PG et al (1977): Opposing central and peripheral effects of atropine on parasympathetic cardiac control
Back to pre-injury function
Pillai R et al
Local unfolding of the HSP27 monomer regulates chaperone activity
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