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Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate
Moreover, this trial was conducted at a private practice and published in an alternative medicine journal, again raising concerns about bias
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The liver is a major site of methionine metabolism and SAM production
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