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ROS are a necessary defense system to combat microbial respiratory infections (Lambeth, 2004), but oxidative stress and the excessive production of ROS by numerous cells including monocytes and macrophages, neutrophils, as well as pulmonary endothelial and epithelial cells play a major role in the development of ARDS and its complications during COVID-19 infections (Meftahi et al., 2021)
The researchers found a similar effect in humans, though they say more study is needed
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
Cells 181, 969977
Resistance to viral diseases positively correlates with the extent of GSH stores (Khomich et al., 2018)
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