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This is why some researchers tolerate once-weekly dosing fine at 15mg but struggled at 5mg, the relative fluctuation is the same but the absolute concentrations at the trough are much higher at 15mg, staying above the therapeutic threshold throughout the cycle
However, unlike Ozempic, Victoza is injected once per day rather than once per week
The other GLP agonists have been looked at for alcohol use disorder, for binge eating disorder, and for a lot of behavioral and impulse control disorders." Andrew Huberman 56% lower risk of new alcohol use disorder diagnoses
Because semaglutide and tirzepatide offer similar cardiovascular protection, choosing the right therapy for patients comes down to individual metrics such as weight-loss goals, tolerability, insurance coverage, and treatment preferences rather than the cardiovascular superiority of either drug.
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