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doi:10.1038/s41598-018-22081-7 (PMID 29483571) Ruf S, Rajagopal S, Kadnur SV, et al
Early trials show significant weight loss and metabolic improvements
These include: Paraesthesia (pins and needles) in hands and feet Difficulty walking or balance problems Memory impairment and cognitive changes Mood disturbances, including depression and irritability Visual disturbances (rare, such as optic neuropathy) Gastrointestinal symptoms such as diarrhoea, constipation, or loss of appetite may also occur, particularly when deficiency results from malabsorption
Future studies should investigate the functional consequences of increased CAR-SIV expression in human cells, specifically examining its role in promoting viral persistence and spread within the insulin secretory granules
If you're low in them, topping them up helps that machinery work properly
