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In the AMY 1 R and AMY 3 R Y37 rAmy interacts with residues in the respective RAMP and the CTR ECD, however the small side chain of P37 Cagri is completely buried by the surrounding CTR ECD residues, forming extensive hydrophobic contacts with W79 ECD and no direct interactions with either RAMP1 (AMY 1 R) or RAMP3 (AMY 3 R), again consistent with the restrictive interactions formed by Pro32 sCT with the CTR ECD
Lushchak VI
This suggests that precise dosing may be less critical than consistent daily administration over an adequate duration
Another randomized trial tested MCTs in 30 university students
Available online at: (Accessed December 30, 2021)
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