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Pheomelanin produces a lighter, yellow-red pigment in place of the dark brown-black eumelanin responsible for hyperpigmentation

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Introduction The aryl hydrocarbon receptor (AhR) protein is a highly conserved ligand-dependent transcription factor that senses xenobiotics to activate detoxifying monooxygenase cytochrome P4501 (CYP1) for degrading ligands to metabolites