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More serious but less common adverse effects require clinical vigilance: Pancreatitis : Patients should be counselled to stop the medication and seek immediate medical attention if they experience severe, persistent abdominal pain radiating to the back [1] [5] Gallbladder disease : Rapid weight loss associated with GLP-1 therapy may increase cholelithiasis risk [1] Hypoglycaemia : Particularly when used alongside insulin or sulphonylureas in diabetes management Diabetic retinopathy : Semaglutide requires caution in patients with pre-existing retinopathy, who should be monitored regularly [1] Renal impairment : Dehydration from gastrointestinal side effects may affect kidney function Specific considerations for individuals with eating disorders include the potential for GLP-1 medications to exacerbate restrictive eating patterns or mask hunger cues in vulnerable individuals

If that is already happening, our guide on how to relieve constipation on GLP-1 covers practical ways to feel better

They were first made for people with type 2 diabetes, but now some are used just for weight loss too

Use Exercise to Shape the Future Health of Young People When you work with young people, their bodies arent just changing, theyre building the foundation theyll carry into adulthood

This process is complemented by the action of glucagon, which maintains plasma glucose levels by promoting glucose production in the liver