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In the inflammatory state, Chemerin inhibits the activity of endothelial nitric oxide synthase (eNOS) and reduces nitric oxide production, further impairing vascular diastolic function, increasing the risk of platelet aggregation and leukocyte adhesion, and promoting vascular inflammation (Lei et al., 2020)

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If you have Hashimotos, this typically also means going on a gluten-free diet, as many studies show a connection between Hashimotos hypothyroidism and a gluten intolerance or celiac disease