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These abnormalities can occur in those that experience weight fluctuations by gaining weight and losing weight frequently due to dieting

The 2025 Am J Gastroenterology: Better Outcomes, Not Worse A separate multicenter analysis, published in American Journal of Gastroenterology (May 2025), extended the question beyond risk to outcomes

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Future trials should examine both induction and maintenance therapy applications, biomarker responses, and endoscopic healing outcomes to establish clinical utility