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1 Oral semaglutide for type 2 diabetes has been available as Rybelsus in a different formulation and set of doses
This choice reflects stability considerations
28 Safety analysis within the same study showed good tolerability and revealed transient local skin reactions as main adverse events
Conclusion The GLP-1 RAs in people with obesity or type 2 diabetes are associated with a significant reduction in all-cause death, alongside an increased risk of pancreatic adverse eventsparticularly acute pancreatitismost pronounced during the first 6 months of treatment
Basic Clin Pharmacol Toxicol (2010) 106(2):8694
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