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Reported side effects include water retention, flushing, headache, tingling in the extremities, elevated IGF-1 levels, impaired glucose tolerance, and injection site reactions including pain and infection risk

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4 15% and Above: Advanced Metabolic Shifts Higher levels of weight loss are associated with: Substantial reduction in intrahepatic fat Enhanced beta-cell function Greater systemic anti-inflammatory effects Long-term mortality benefit observed in surgical cohorts (~1516% weight loss) However, lifestyle interventions often yield 510% sustained reduction in real-world practice