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The key difference from Ozempic: muscle preservation Ozempic and muscle: A meaningful portion of weight lost on semaglutide is lean mass
Hydration matters here too
Nagano et al
It is less directly useful for: Adults at a healthy weight without diabetes, considering GLP-1 as primary cancer prevention
The second generation somatostatin analog pasireotide has been shown to induce impaired glucose tolerance, overt diabetes or worsen glycemic control especially in patients with pre-existing disturbed glucose metabolism (52)
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