Wegovy(semaglutide) is now available as an FDA-approved GLP-1 pill for weight loss
In general, essential fatty acid deficiency (i.e., deficiency of both ALA and LA) has been observed only in patients with chronic fat malabsorption, cystic fibrosis, or those on parenteral nutrition without PUFA (86, 95) (see the article on Essential Fatty Acids)
I have gotten injections for almost 2 years, but I have to fight for it every month
9 Research gaps and future priorities 9.1 Reproductive-oriented RCTs: shifting from metabolic surrogates to hard endpoints To date, most GLP-1RA trials in PCOS have been designed around metabolic efficacy (weight change and insulin-resistance/glycaemic indices) as the primary outcomes, with reproductive outcomesovulation, clinical pregnancy, and live birthreported inconsistently and often as secondary or exploratory measures
Weight loss itself can improve insulin resistance and sometimes reduce TSH levels naturally, so baseline measurements let you distinguish medication effects from weight-loss effects