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1 Introduction Thyroid disorders are a unique intersection of endocrine and neurological health, and they are among the most widespread endocrine diseases worldwide ( The effects of thyroid disorders on the central nervous system manifest across the entire lifespan: congenital hypothyroidism and iodine deficiency impair neurodevelopment in early life
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Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern
However, response may vary: Higher baseline weight Individuals starting at higher body weights may experience: Slower percentage weight loss initially Need for full maintenance doses to achieve optimal effects Potentially better tolerance of higher doses Lower baseline weight Those with lower starting weights might: Achieve therapeutic goals at submaximal doses (e.g., 2.4 mg vs
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