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In a study of transgenic mice with a Kras G12D mutation which induces PanINs and eventually pancreatic cancer, treatment with exendin-4 increased higher grade PanIN lesions (35, 38)
The major results are summarized and extended in the following text
For treatment over several days or in mild cases, 300 to 600 mg per day should be injected into a muscle or continuously injected into a vein
DOI: 10.1016/S0140-6736(23)01053-X Wilding, J.P.H., et al
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