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Overall, irreparable damage to membranous organelles, spindle microtubules, cellular DNA, and the heat shock system itself leads to profound dysfunction of gametes and embryos and even apoptotic cell death, all of which adversely impact fertility (84, 85, 107, 109, 110, 152, 153)

What concerns me most is not just where the medication comes from

coined the term ferroptosis to describe the cell death of cancer cells with RAS mutations induced by erastin [17]

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