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Second, there was no control group, so we cant rule out the possibility that the patients would have improved over time anyway

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When to Seek Professional Guidance Consult a healthcare professional if: You suspect B12 deficiency You experience neuropathy symptoms in the feet You want to explore B12 nerve-targeted injection programmes B12 injections in the foot and ankle are most effective when part of a comprehensive neuropathy care plan , including nutrition, lifestyle, and medical support