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Its very sad because its been so instrumental to my career, and I had hoped that it would be instrumental to the career of many of our junior faculty, Forrest said.
In rats subjected to experimental hypoxia, a significant stress-mediated reduction in both the rate of phosphorylated respiration (V3, a 20% decrease) and the rate of ADP phosphorylation (ADP/t, a 31% decrease) was observed in brain mitochondria
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Strikingly, researchers further found CB-GLP-1 promoted the mitophagy pathway mediated by PINK1/Parkin [90], a crucial mechanism in mitochondrial quality control
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