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Semaglutide activates only the GLP-1 pathway
Chronic semaglutide treatment increases body weight-adjusted energy expenditure and locomotor activity Absolute EE decreased rapidly following the first semaglutide treatment and gradually continued to decrease below what is observed in vehicle-treated mice ( Figure 3A-B )
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Tirzepatide consistently outperforms semaglutide in head-to-head trials , producing 6%--7% more weight loss
Given that the demand for the antioxidant had spiked during COVID, they needed to ramp up sales and protect market share by finding a solution fast
