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Individuals carrying specific GLP1R polymorphisms may exhibit heightened insulin secretion in response to semaglutide, increasing baseline hypoglycemia risk and warranting more aggressive concomitant medication de-escalation

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Nature (2003) 425:903

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Resistance training prevents muscle loss induced by caloric restriction in obese elderly individuals: a systematic review and meta-analysis

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If you take insulin or sulfonylureas along with semaglutide, monitor your blood glucose closely when your food intake is reduced, as you may be at risk for hypoglycemia

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