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Gut microbiota regulates CCK secretion through interactions between metabolites and jejunal I-cells: SCFAs and bile acids enhance CCK synthesis by activating FFAR2 and TGR5 receptors on jejunal I-cells
5 Different dosage forms of SalB The absolute bioavailability of SalB is only 3.9% after oral administration of 50 mg/kg SalB to rats (Zhou et al., 2009)
Public literature is concentrated in Phase 12 trial reports and preclinical pharmacology
Li A, Su X, Hu S, Wang Y
In a real-world observational study of over 2,000 type 2 diabetes patients, dulaglutide showed a mean body-weight reduction of ~2.9 kg
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