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AOD-9604: A growth hormone fragment focused on fat loss

Inhibition or down-regulation of GDH expression leads to a reduction in -KG production, which in turn affects the normal physiological activity of the tumour in a manner that reduces energy supply

This is not uncommon and may be related to the body adjusting to a rapid increase in B12 availability, especially in patients who were significantly deficient

N Engl J Med 384(12):11131124 Osaka T, Endo M, Yamakawa M, Inoue S (2005) Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system

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