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All of Us illustrates that federally funded, purpose-built diversity recruitment at a national scale can substantially outperform the diversity metrics typical of pharmaceutical sponsor-run trials, though the program is a research cohort rather than an interventional drug trial, a distinction that limits direct comparison

Neurology (2009) 72(Suppl 4):S1136.10.1212/WNL.0b013e3181a1d44c 11 de GasparoMCattKJInagamiTWrightJWUngerT

Results demonstrated that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo. Critically, the peptide produced no clinically significant alterations in IGF-1 levels, no glucose intolerance or insulin resistance, and no anti-AOD9604 antibodies in any participant

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Injection site selection balances convenience with proximity to target tissues