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Hydroxocobalamin, the form of B12 most commonly used in UK clinical practice, may cause a harmless pink or red discolouration of urine

As it was previously demonstrated that lysine lactylation was induced by neural excitation, a key molecular mechanism for the development of epilepsy [96], with the detailed results showing the positive association of increase of lysine lactylation and the expression of the immediate-early gene marker of neuronal activity c-Fos [97], it is hypothesized that histone delactylation by HDAC1-3 may inhibit the development of epilepsy and prevent seizures

The Dual-Glo Luciferase Assay System was from Promega

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Wnt/ -catenin Signaling Pathway Wnt/-catenin pathway is a vital pathway regulating in regulating cell proliferation, apoptosis and tissue repair