Side effects are uncommon but may include mild gastrointestinal discomfort in some individuals
Higher drug levels mean stronger insulin secretion in response to meals, which could theoretically cause hypoglycemia
For example, one study found that giving people with asthma 200 mcg of selenium per day reduced their use of the corticosteroid medications used to control their symptoms ( However, research in this area is conflicting, and larger studies are needed to fully understand seleniums role in the development and treatment of asthma ( Summary Selenium may benefit people with asthma due to its ability to lower inflammation in the body
Based on available literature, the oral mass dose to match parenteral efficacy at systemic endpoints appears to be 5-10 higher
Important safety considerations include a boxed warning for medullary thyroid carcinoma risk, monitoring for pancreatitis (severe abdominal pain), gallbladder disease, and potential hypoglycemia when used with insulin or sulfonylureas