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Protocols describe an empty stomach at least 2-3 hours after eating, with food avoided for 1 hour post-injection

Pharmacol Res 155:104689

Both injectable and nasal spray forms are used in practice, with the choice often depending on patient preference, treatment adherence, and desired intensity of effect

Melanotan 1 (afamelanotide) is MC1R-preferential : it is comparatively focused on the pigmentation receptor, which is precisely why its clinically observed effects center on skin darkening and photoprotection rather than on sexual function or appetite

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