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On one hand, by optimizing organoid construction techniques and integrating cutting-edge technologies such as single-cell sequencing and gene editing, the developmental accuracy and functional integrity of organoids can be further improved

Furthermore, mice develop insulin resistance after vagotomy [61]

Larger effects in studies enrolling older samples ( 60 years) were observed, but the remaining between-study findings warrant prospective confirmation

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Regarding FEX (BCP15784, BioChemPartner) treatment, mice were gavaged with 100 mg/kg FEX every day for 5 days