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Elevated ROS levels can trigger NLRP3 inflammasome activation, subsequent caspase-1 activation and gasdermin D (GSDMD) cleavage, ultimately inducing pyroptosis
[1] Skin lightening or bleaching refers to the cosmetic practice of applying depigmenting agents not as treatment for hyperpigmentation but with the deliberate aim of achieving a lighter skin colour
doi: 10.1016/j.chom.2018.05.003 49
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