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A: Degradation can sometimes be detected by changes in the appearance of the peptide solution (e.g., cloudiness, precipitation) or a loss of expected biological activity
Injecting heavily oxidized/glycated LDL reproduces human DR features: vascular leakage, ERG dysfunction, vascular endothelial growth factor (VEGF) overexpression, inflammation, ER stress and apoptosis (48, 53)
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