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Compounds such as BPC-157 or growth hormone-releasing peptides have been studied primarily in animal models or small, low-quality human studies, and there is currently no high-quality evidence supporting their use for weight management in humans

GLP-1RAs not only have glucose-lowering but also greater weight-loss effects as discussed in detail in a previous literature [26], the results of SELECT also suggest the weight-loss effect as an important factor explaining the cardiovascular protective effects of GLP-1RAs regardless of diabetes

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