How Might PDA Work
Availability depends on provider evaluation, state participation, pharmacy requirements, and clinical eligibility
If all appeals fail and you still need the medication, your options are paying cash for branded GLP-1s (Wegovy retail is around $1,350 per month, Zepbound around $1,060), using the manufacturer savings programs from Novo Nordisk or Eli Lilly, or pursuing compounded semaglutide or tirzepatide through a licensed telehealth provider
And you should still feel some hunger on semaglutide just less of it
Still, they work through fundamentally different mechanisms: AOD-9604 is a modified fragment of human growth hormone designed to isolate its lipolytic (fat-metabolizing) region without triggering the broader GH/IGF-1 response, while Tesamorelin is a growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary to increase natural GH production