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Although the role of semaglutide in patients with type 2 diabetes is well-established, its use among adults without type 2 diabetes mellitus remains unclear
The research published in preclinical models shows decreased rewarding effects across multiple pleasure categories when GLP-1 signaling increases
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Poly-agonists : Drugs combining GLP-1 with other hormones (GIP, glucagon, amylin) to potentially increase weight loss
Type 2 diabetes substantially increases the risk of cardiovascular events, and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been shown to reduce major adverse cardiovascular outcomes
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