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10.1016/S1875-5364(23)60399-1 38 HuanD
PARP inhibitors downregulate SLC7A11 in a p53-dependent manner, reducing GSH biosynthesis and promoting lipid peroxidation and ferroptosis
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This balance is essential to uphold cellular function and viability, and its disruption links to devastating human diseases
For instance, a person dealing with depression may benefit from group activities that encourage social interaction, which can be crucial for building connections and finding joy again
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