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Grimes PE, Nashawati R
10.1186/s12888-023-05481-6 4
The Gene Expression Revolution: 4,000+ Genes The most striking finding in GHK-Cu research came not from traditional biochemistry but from genomic analysis
It may also slow down aging and improve recovery
Among the E3 ligases, MuRF1 and Atrogin-1/MAFbx are canonical atrogenes strongly upregulated during catabolic stress (e.g., denervation, fasting, glucocorticoid exposure, cancer cachexia), and are indispensable for UPS-mediated muscle degradation
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