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When it persists longer than necessary, it can lead to severe health problems and chronic pain
It also plays an indirect role in energy metabolism
Much of what is sold online is labeled research only, and the purity of those products is highly variable, with independent testing repeatedly finding under-dosed, degraded, or mislabeled peptides across the unregulated market
Quintessentially, the main clinical manifestations are poor bowel movements (i.e., constipation, colic, abdominal distension, and fuzzy indigestion) and blood in the stool