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Defined: Glutathione Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea, preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals.[2] It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine (which is attached by a normal peptide linkage to a glycine)
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S., Salama, A
Functionally, TXNIP acts as a tumor suppressor through its downregulation in malignant cells, where it concurrently suppresses proliferation and metastatic potential and promotes apoptotic pathways (9193)
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