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In clinical trials, discontinuation rates due to gastrointestinal adverse effects ranged from 3-7%, indicating that whilst most patients can tolerate these symptoms, they can be sufficiently troublesome to necessitate treatment cessation in some cases

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Kumar says the biggest problem with these medicines right now is access: "There are people paying out of pocket, sometimes up to $1,200 a month

Joint health: synovial inflammation degrades cartilage