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FDA has also discussed ipamorelin acetate safety concerns in compounding, including immunogenicity risks related to aggregation or peptide-related impurities and the complexity of characterization
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While reducing treatment frequency from daily to weekly is associated with improved patient adherence, there is still room for improvement to reduce treatment burden and improve patience compliance (Figure 1A) ( 2426 )
10.1073/pnas.1116531109 157 VaculkM.KonlechnerC.LangerI.AdlassnigW.PuschenreiterM.LuxA.et al (2012)
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