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doi: 10.1210/jc.2014-4491 12 AndraosJMuharHSmithSR

however, it is not known whether this occurs at clinically relevant doses in humans

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In patients with type 2 DM, GLP-1R agonists have demonstrated a reduction in circumferential strain and improvement in markers of diastolic function, a key component of diabetic cardiomyopathy and the risk of developing heart failure