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Our practice operates on a strict infection control policy and following anti-septic swabbing of the injection area the B12 injection will be administered (typically in the side upper arm / shoulder region)
PMCID: PMC7690794
If you are currently using sublingual or oral forms of B12 and you are getting symptomatic relief then I wouldnt recommend changing up your method of administration
Administering the Injection Choose the Injection Site : IM Injection Sites : Common sites include the deltoid muscle (upper arm), gluteus maximus (buttocks), and vastus lateralis (thigh)
The 2025 systematic review noted that despite increasing clinical use, this level of evidence does not yet exist
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