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Tirzepatide is part of a group of medications called GLP-1 receptor agonists , which help people with type 2 diabetes and obesity by controlling blood sugar and promoting weight loss
Thus, the designed GLP-1 albumin fusions stimulate glucose-dependent insulin secretion in a GLP-1R-dependent manner
These results suggest that the decline in glutathione in neurons is more critical for the brain atrophy than that in astrocytes
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