doi: 10.1080/15563650.2017.1291945 [PubMed] 29423816 Yarema M, Chopra P, Sivilotti MLA, Johnson D, Nettel-Aguirre A, Bailey B, Victorino C, Gosselin S, Purssell R, Thompson M, Spyker D, Rumack B
If your skin is not very sensitive, and you want to maximize the benefits of vitamin C, you can use it both in the morning and at night
To optimize cellular and mitochondrial performance, (1) niacins (vitamin B3) must be consistently supplied in the diet (hence the designation as a vitamin) and (2) nicotinamide (NAM) generated by NAD + consuming reactions must be constantly salvaged and recycled to NAD +
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However, in the face of chronic, complex illness, this vital defense mechanism can become profoundly overwhelmed and depleted