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Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma

Last reviewed: June 17, 2026 Last updated: June 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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Abbreviations GLP-1: Glucagon Like Peptide-1 CV: Cardio Vascular DPP-4: DiPeptidylPeptidase-4 USFDA: United States Food & Drug Administration Aib: 2-Aminoisobutyric acid SNAC: Sodium-N-[8-(2-hydroxybenzoyl)amino]caprylate SUSTAIN: Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes FPG: Fasting Plasma Glucose HOMA-B: Homeostasis model assessment of -cell function ER: Extended release DXA: Dual energy X-ray Absorptiometry OAD: Oral Antidiabetic Drugs SGLT-2: Sodium GLucose co-Transporter-2 SMBG: Self-Monitoring of Blood Glucose PIONEER: Peptide Innovation for Early Diabetes Treatment EMA: European Medicines Agency References Garber AJ, Abrahamson MJ, Barzilay JI, Blonde L, Bloomgarden ZT, Bush MA, Dagogo-Jack S, DeFronzo RA, Einhorn D, Fonseca VA, Garber JR, Garvey WT, Grunberger G, Handelsman Y, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, Rosenblit PD, Umpierrez GE

Taylor sets realistic expectations and tracks your progress throughout the program