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It can be helpful in the treatment of conditions like liver disease and cancer, where detoxification is a critical component of treatment
Guidelines recommend GLP-1 medications with proven cardiovascular benefit for diabetic patients with or at high risk for cardiovascular disease
Landmark studies include STEP for semaglutide (NEJM, 2021), SURMOUNT for tirzepatide (NEJM, 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM, 2024)
The treatment lowers blood sugar levels making it ideal for individuals who are prediabetic or have type 2 diabetes
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