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Semaglutide, the active ingredient in Ozempic and Wegovy, follows a different escalation schedule: 0.25mg for four weeks, 0.5mg for four weeks, 1mg for four weeks, 1.7mg for four weeks, and finally 2.4mg for maintenance

In contrast, branded and generic medicines are rigorously tested to gain FDA approval and facilities that manufacture FDA-approved products are inspected before they start production as well as other times during the approval process

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It is that current UK guidance sees tirzepatide as a very strong obesity treatment and, in the evidence NICE reviewed, stronger than semaglutide overall for weight loss