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To discard a putative strain dependence of this phenotype, we constructed the ahpD in a D39 genetic background, the ancestral strain for R6 and R801 strains, and we found the same H 2 O 2 susceptibility observed in the R801 strain (Fig S3), and this will be discussed later

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while they strongly suggest that methionine fuels glutathione synthesis, the precise metabolic flux through the methionine pathway under cystine-limited conditions remains to be quantified using isotope tracing

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