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What the Evidence Shows The clinical trial data for GLP-1 medications is among the strongest ever produced for a non-surgical weight loss intervention: Ozempic (semaglutide 12mg): Mean weight loss of approximately 1012% of body weight over 4068 weeks in SUSTAIN trials Wegovy (semaglutide 2.4mg): Mean weight loss of 1517% of body weight over 68 weeks in STEP trials Mounjaro (tirzepatide 15mg): Mean weight loss of 2022% of body weight over 72 weeks in SURMOUNT trials For context, older weight loss medications typically produced 58% weight loss

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Dosage / Direction subcutaneous injection in the abdomen , thigh , or upper arm

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