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If you inject only once a week or worse, once a month youll barely see any improvement

Most patients who experience significant relief will notice it almost immediately

Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)

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This repeated injury can lead to esophagitis, characterized by inflammation, erosion, and ulceration of the tissue