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Over 68 weeks, with a starting dose of 2 mg escalated every 4 weeks: 9 mg dose: 26.4% average body weight reduction (29.1 kg / 64.2 lbs) 12 mg dose: 28.7% average body weight reduction (32.3 kg / 71.2 lbs) Placebo: 2.1% average body weight reduction The milestone achievements tell an even more compelling story

Those with prediabetes Emerging evidence suggests that GLP-1 drugs could help prevent or delay the onset of Type 2 diabetes in individuals with prediabetes by improving insulin sensitivity and promoting weight loss

However, some clinicians prefer a more conservative approach even from high tirzepatide doses, starting semaglutide at 0.5 mg and titrating up every 4 weeks

No, B12 supplements don't interfere with Ozempic's effectiveness

Gonzalez-Quevedo, D., Martinez-Medina, I., Campos, A., Campos, F